Flights from Des Moines to destinations worldwide

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Some of our direct flights from Des Moines .View All Destinations

Scheduled Flights

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Today's Cheap Flights from Airlines and Online Travel Agents!

Las Vegas from $90

DSM - LAS - (Sep 15 - Sep 19)

Sanford-Orlando from $92

DSM - SFB - (Sep 10 - Sep 12)

Orlando from $164

DSM - MCO - (Sep 29 - Oct 6)

Charlotte from $221

DSM - CLT - (Oct 13 - Oct 23)

Moline-Quad Cities from $229

DSM - MLI - (Sep 16 - Sep 20)

Appleton from $239

DSM - ATW - (Sep 16 - Sep 20)

Greensboro from $249

DSM - GSO - (Mar 24 - Mar 28)

Corpus Christi from $255

DSM - CRP - (Oct 28 - Nov 4)

Panama City Beach from $263

DSM - ECP - (Nov 4 - Nov 10)

Fresno from $290

DSM - FAT - (Nov 1 - Nov 5)

Palm Springs from $290

DSM - PSP - (Nov 11 - Nov 13)

Rochester from $766

DSM - RST - (Sep 3 - Sep 4)

Recently found airline fares via KAYAK. Prices may change in real time.

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Rental Cars

Easily compare prices from all major rental car companies — whether you're flying out of Des Moines or arriving at your destination.

Rental Cars

Vacation Packages

Discover unbeatable vacation deals from Des Moines or explore dream getaways around the world.

Vacation Packages

Hotels & Accommodations

Find the perfect place to stay—near Des Moines or wherever your travels take you.

Hotels & Accommodations

Save Big on Flights from Des Moines

Today's Cheap Flights from Airlines and Online Travel Agents!

Las Vegas from $90

DSM - LAS - (Sep 15 - Sep 19)

Sanford-Orlando from $92

DSM - SFB - (Sep 10 - Sep 12)

Orlando from $164

DSM - MCO - (Sep 29 - Oct 6)

Charlotte from $221

DSM - CLT - (Oct 13 - Oct 23)

Moline-Quad Cities from $229

DSM - MLI - (Sep 16 - Sep 20)

Appleton from $239

DSM - ATW - (Sep 16 - Sep 20)

Greensboro from $249

DSM - GSO - (Mar 24 - Mar 28)

Corpus Christi from $255

DSM - CRP - (Oct 28 - Nov 4)

Panama City Beach from $263

DSM - ECP - (Nov 4 - Nov 10)

Fresno from $290

DSM - FAT - (Nov 1 - Nov 5)

Palm Springs from $290

DSM - PSP - (Nov 11 - Nov 13)

Rochester from $766

DSM - RST - (Sep 3 - Sep 4)

Recently found airline fares via KAYAK. Prices may change in real time.

Scheduled Flights

Some of our direct flights from Des Moines .View All Destinations

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Scheduled Flights

Scheduled Flights

Save Big on Flights from Des Moines

Save Big on Flights

Save Big on Flights from Des Moines

Scheduled Flights